Friday Night Lights
Mostly shows well regarded by critics, by and large. I've seen House maybe a dozen or so times, and Hugh Laurie is great. I saw Dexter a few times and liked it a bit. I watch Boston Legal when I'm looking for wry topical humor. Plus any Shatnerologist has to watch Denny Crane from time to time. But, if I were voting off of this list, I'd be torn between Lost and Mad Men. I'd probably vote for Lost. But, Mad Men is going to win. Unless all the voters are on drugs, in which case Grey's Anatomy wins.
While I was reading AICN I noticed that Harry Knowles reports that he had a visit with J.J. Abrams and was shown a few roughly cut scenes from Star Trek. It sounds promising.